Friday 27 August 2010

HALLUCINOGENIC PLANTS (PART 29)


SINICUICHI (Heimia salicifolia) is a poorly understood but fascinating auditory hallucincogen of central Mexico. Its leaves, slightly wilted, are crushed and soaked in water. The resulting juice is put in the sun to ferment into a slightly intoxicating drink that causes giddiness, darkening of the surroundings, shrinkage of the world, and drowsiness or euphoria. Either deafness or auditory hallucinations may result, with voices or sounds distorted and seeming to come from a distance. Partakers claim that unpleasant after- effects are rare, but excessive drinking of the intoxicant can be quite harmful.

Sinicuichi is a name given also to other plants that are important both medically and as intoxicants in various parts of Mexico. Other intoxicating sinicuichis are Erythrina, Rhynchosia, and Piscidia, but Heimia salicifolia commands the greatest respect. With the closely related H. myrtifolia, it has interesting uses in folk medicine. Only in Mexico, however, is the hallucinogenic use important.

Heimia belongs to the loosestrife fomily, Lythroceae, and represents an American genus of three hardly distinguishable species that range in the highlands from southern United States to Argentina. Presence of hallucinogenic principles was unknown in this family, but chemists have recently found six alkaloids in Heimia salicifolia. They belong to the quinolizidine group. One, cryogenine or vertine, appears to be the most active, although the hallucinogenic effects following ingestion of the total plant have not yet been duplicated by any of the alkaloids isolated thus far. This provides us with another example of the often appreciable difference between the effects of drugs taken as natural products and the effects of their purified chemical constituents.


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HALLUCINOGENIC PLANTS (PART 28)


SHANSHI (Coriaria thymifolia) is a widespread Andean shrub long recognized as very poisonous to cattle. It has recently been reported as one of the plants used as an hallucinogen by peasants in Ecuador. Shanshi is their name for the plant. The fruits are eaten for their intoxicating effects, which include the sensation of flight. The weird effects are due possibly to an unidentified glycoside, but the chemistry of this species is still poorly understood. Shanshi is one of 15 species of Coriaria, most of which are shrubs. They are found in the mountains from Mexico to Chile, from the Mediterranean area eastward to Japan, and also in New Zealand. Corioria is the only known genus in the family, Corioriaceae.



HALLUCINOGENIC PLANTS (PART 27)


ANOTHER KIND OF CAAPI is prepared from Tetrapteris methistica, a forest vine also belonging to the family Malpighioceae. One group of Maku Indians of the northwesternmost part of the Brazilian Amazon prepares a cold-water drink from the bark. There is no other plant ingredient. The drink is very bitter and has an unusual yellow hue. This may be the " second kind" of caapi mentioned by several explorers as caapi-pinima, meaning "painted caapi." Although T. methystica produces effects identical with those of Banisteriopsis caapi, we still know nothing of its chemistry. However, it is closely related to Banisteriopsis and there is every probability that similar or identical alkaloids are present. There are 90 species of Tetrapteris - vines and small trees found throughout the humid American tropics.



Thursday 26 August 2010

HALLUCINOGENIC PLANTS (PART 26)


PLANTS ADDED TO AYAHUASCA by some Indians in the preparation of the hallucinogenic drink are amazingly diverse and include even ferns. Several are now known to be active themselves and to alter effectively the properties of the basic drink. Among these are Datura suaveolens (p. 145) and a species of Brunfelsia (p. 140)—both members of the nightshade family, Solanaceae, and both containing active principles.

Two additives, employed over a wide area by many tribes, are especially significant. The leaves (but not the bark) of a third species of Banisteriopsis - B. rusbyana - are often added to the preparation "to lengthen and brighten the visions." Called oco-yajé in the westernmost Amazon region of Colombia and Ecuador, the liana is cultivated for this purpose, along with B. caapi and B. inebrians.

Over a much wider area, including Amazonian Brazil, Colombia, Ecuador, and Peru, the leaves of several species of Psychotria - especially P. viridis - are added. This 20-foot forest treelet belongs to the coffee family, Rubioceae. Like B. rusbyana, it has been found recently to contain the strongly hallucinogenic N. N-dimethyltryptamine.


HALLUCINOGENIC PLANTS (PART 25)


EFFECTS of drinking ayahuasca range from a pleasant intoxication with no hangover to violent reactions with sickening after - effects. Usually there are visual hallucinations in color. In excessive doses, the drug brings on nightmarish visions and a feeling of reckless abandon. Consciousness is usually not lost, nor is there impairment of the use of the limbs. In fact, dancing is a major part of the ayahuasca ceremony in some tribes. The intoxication ends with a deep sleep and dreams. An ayahuasca intoxication is difficult to describe. The effect of the active principles varies from person to person. In addition, preparation of the drink varies from one region to another, and various plant additives may also alter the effects.


CEREMONIAL USES of ayahuasca are of major importance in the lives of South American Indians. In eastern Peru, medicine men take the drug to diagnose and treat diseases. In Colombia and Brazil, the drug is employed in deeply religious ceremonies that are rooted in tribal mythology. In the famous Yurupari ceremony of the Tukanoan Indians of Amazonian Colombia - a ceremony that initiates adolescent boys into manhood - the drug is given to fortify those who must undergo the severely painful ordeal that forms a part of the rite. The intoxication of ayahuasca or caapi among these Indians is thought to represent a return to the origin of all things: the user "sees" tribal gods and the creation of the universe and of man and the animals. This experience convinces the Indians of the reality of their religious beliefs, because they have "seen" everything that underlies them. To them, everyday life is unreal, and what caapi brings them is the true reality.


CHEMICAL STUDIES of the two ayahuasca vines have suffered from the botanical confusion surrounding them. However, it appears that both species owe their hallucinogenic activity primarily to harmine, the major ,B-carboline alkaloid in the plants. Harmaline and tetrohydroharmine, alkaloids present in minor amounts, may also contribute to the intoxication. Early chemical studies isolated these several alkaloids but did not recognize their identity. They were given names as "new" alkaloids. One of these names—telepathine—is an indication of the widespread belief that the drink prepared from these vines gave the Indian medicine men telepathic powers.

HALLUCINOGENIC PLANTS (PART 24)


AYAHUASCA and CAAPI are two of many local names for either of two species of a South American vine: Banisteriopsis caapi or B. inebrians. Both are gigantic jungle lionas with tiny pink flowers. Like the approximately 100 other species in the genus, their botany is poorly understood. They belong to the family Malpighiaceae. An hallucinogenic drink made from the bark of these vines is widely used by Indians in the western Amazon—Brazil, Colombia, Peru, Ecuador, and Bolivia. Other local names for the vines or the drink made from them are dopa, natema, pinde, and yaje. The drink is intensely bitter and nauseating. In Peru and Ecuador, the drink is made by rasping the bark and boiling it. In Colombia and Brazil, the scraped bark is squeezed in cold water to make the drink. Some tribes add other plants to alter or to increase the potency of the drink. In some parts of the Orinoco, the bark is simply chewed. Recent evidence suggests that in the northwestern Amazon the plants may be used in the form of snuff. Ayahuasca is popular for its "telepathic properties," for which, of course, there is no scientific basis.




EARLIEST PUBLISHED REPORTS of ayahuasca date from 1858 but in 1851 Richard Spruce, an English explorer, had discovered the plant from which the intoxicating drink was made and described it as a new species. Spruce also reported that the Guahibos along the Orinoco River in Venezuela chewed the dried stem for its effects instead of preparing a drink from the bark. Spruce collected flowering material and also stems for chemical study. Interestingly, these stems were not analyzed until 1969, but even after more than a century, they gave results (p. 103) indicating the presence of alkaloids.

In the years since Spruce's discovery, many explorers and travelers who passed through the western Amazon region wrote about the drug. It is widely known in the Amazon but the whole story of this plant is yet to be unraveled. Some writers have even confused ayahuasca with completely different narcotic plants.


HALLUCINOGENIC PLANTS (PART 23)


PIULE (several species of Rhynchosia) have beautiful red and black seeds that may have been valued as a narcotic by ancient Mexicans. What appear to be these seeds have been pictured, together with mushrooms, falling from the hand of the Aztec rain god in the Tepantitla fresco of A.D. 300-400 (see p. 59), suggesting hallucinogenic use. Modern Indians in southern Mexico refer to them as piule, one of the names also applied to the hallucinogenic morning-glory seeds.

Seeds of some species of Rhynchosia have given positive alkaloid tests, but the toxic principles hove still not been characterized.

Some 300 species of Rhynchosia, belonging to the bean family, Leguminosae, are known from the tropics and subtropics. The seeds of some species are important in folk medicine in several countries.